Medicalization and Mental Health: The Role of Psychotropic Drugs in Psychological Suffering

Authors

  • Gema Dioselina Anchundia Talledo State University of Milagro image/svg+xml Author

DOI:

https://doi.org/10.64747/4wfywd19

Keywords:

Psychotropic drugs, Medicalization, Mental suffering, Psychiatry, Narratives

Abstract

The expansion of diagnostic categories and pharmacological responses has transformed how societies interpret and address psychological suffering. This critical narrative review aimed to analyze the role of psychotropic drugs within mental-health medicalization processes while distinguishing clinically justified use from overmedicalization. Academic publications indexed in PubMed/MEDLINE and SciELO, official documents from the World Health Organization and the Pan American Health Organization, and verified DOI records were consulted. Priority was given to systematic reviews, meta-analyses, guidelines, and Latin American studies published up to August 2026. The synthesis showed that antidepressants and antipsychotics may provide meaningful benefits for specific indications, although average effectiveness, tolerability, and acceptability vary across individuals and contexts. Risks were also identified, including adverse effects, prolonged treatment without sufficient review, discontinuation symptoms, and limited participation in treatment decisions. Evidence on social determinants and community care indicated that reducing distress to an individual disorder may obscure poverty, violence, precarious employment, discrimination, and biographical trajectories. The review concludes that the central problem is not the existence of psychotropic medicines, but their automatic, exclusive, or decontextualized use. A balanced practice requires careful diagnostic assessment, informed consent, shared decision-making, monitoring of benefits and harms, access to psychological and social interventions, and rights-based community services.

References

Alonso-Pedrero, L., Bes-Rastrollo, M., & Marti, A. (2019). Effects of antidepressant and antipsychotic use on weight gain: A systematic review. Obesity Reviews, 20(12), 1680-1690. https://doi.org/10.1111/obr.12934

Bandarra, A., Costa, C., Angelova, K., Leonardo, L., & Espírito-Santo, M. (2024). Exploring adverse drug reactions in psychotropic medications: A retrospective analysis of Portuguese pharmacovigilance data. Healthcare, 12(8), 808. https://doi.org/10.3390/healthcare12080808

Busfield, J. (2017). The concept of medicalisation reassessed. Sociology of Health & Illness, 39(5), 759-774. https://doi.org/10.1111/1467-9566.12538

Camino, A., Chávez, C., Hernández, V., Villarroel, C., Romero Romero, P., & Guevara, C. (2017). Análisis económico del costo de los medicamentos usados en patologías psiquiátricas: el tercio de los ingresos de un paciente se consumen en fármacos. Revista de la Facultad de Ciencias Médicas (Quito), 42(2). https://doi.org/10.29166/ciencias_medicas.v42i2.1497

Castro, M. A. (2024). El psicofármaco en Chile: entre el tratamiento psiquiátrico, los efectos adversos y el sufrimiento psíquico. Rumbos TS, 19(33), 105-134. https://doi.org/10.51188/rrts.num33.933

Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., Leucht, S., Ruhe, H. G., Turner, E. H., Higgins, J. P. T., Egger, M., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. P. A., & Geddes, J. R. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis. The Lancet, 391(10128), 1357-1366. https://doi.org/10.1016/S0140-6736(17)32802-7

Conrad, P. (1992). Medicalization and social control. Annual Review of Sociology, 18, 209-232. https://doi.org/10.1146/annurev.so.18.080192.001233

Cuijpers, P., Noma, H., Karyotaki, E., Vinkers, C. H., Cipriani, A., & Furukawa, T. A. (2020). A network meta-analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression. World Psychiatry, 19(1), 92-107. https://doi.org/10.1002/wps.20701

Duncan, E., Best, C., & Hagen, S. (2022). Shared decision-making interventions for people with mental health conditions. Cochrane Database of Systematic Reviews, 10, CD007297. https://doi.org/10.1002/14651858.CD007297.pub3

Ferreira, J., Rossi, F., Jirón, M., de Lima, I., Siani-Morello, M., Detoni, V., & Leira, L. (2021). Descrição do consumo de psicofármacos na atenção primária à saúde de Ribeirão Preto, São Paulo, Brasil. Cadernos de Saúde Pública, 37(1), e00060520. https://doi.org/10.1590/0102-311X00060520

Henssler, J., Schmidt, Y., Schmidt, U., Schwarzer, G., Bschor, T., & Baethge, C. (2024). Incidence of antidepressant discontinuation symptoms: A systematic review and meta-analysis. The Lancet Psychiatry, 11(7), 526-535. https://doi.org/10.1016/S2215-0366(24)00133-0

Hofmann, B. (2016). Medicalization and overdiagnosis: Different but alike. Medicine, Health Care and Philosophy, 19, 253-264. https://doi.org/10.1007/s11019-016-9693-6

Huhn, M., Nikolakopoulou, A., Schneider-Thoma, J., Krause, M., Samara, M., Peter, N., Arndt, T., Bäckers, L., Rothe, P., Cipriani, A., Davis, J., Salanti, G., & Leucht, S. (2019). Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: A systematic review and network meta-analysis. The Lancet, 394(10202), 939-951. https://doi.org/10.1016/S0140-6736(19)31135-3

Kaczmarek, E. (2019). How to distinguish medicalization from over-medicalization? Medicine, Health Care and Philosophy, 22(1), 119-128. https://doi.org/10.1007/s11019-018-9850-1

Leucht, S., Tardy, M., Komossa, K., Heres, S., Kissling, W., Salanti, G., & Davis, J. M. (2012). Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: A systematic review and meta-analysis. The Lancet, 379(9831), 2063-2071. https://doi.org/10.1016/S0140-6736(12)60239-6

Lund, C., Brooke-Sumner, C., Baingana, F., Baron, E. C., Breuer, E., Chandra, P., Haushofer, J., Herrman, H., Jordans, M., Kieling, C., Medina-Mora, M. E., Morgan, E., Omigbodun, O., Tol, W., Patel, V., & Saxena, S. (2018). Social determinants of mental disorders and the Sustainable Development Goals: A systematic review of reviews. The Lancet Psychiatry, 5(4), 357-369. https://doi.org/10.1016/S2215-0366(18)30060-9

Maund, E., Stuart, B., Moore, M., Dowrick, C., Geraghty, A. W. A., Dawson, S., & Kendrick, T. (2019). Managing antidepressant discontinuation: A systematic review. Annals of Family Medicine, 17(1), 52-60. https://doi.org/10.1370/afm.2336

Moncrieff, J., Cooper, R. E., Stockmann, T., Amendola, S., Hengartner, M. P., & Horowitz, M. A. (2022). The serotonin theory of depression: A systematic umbrella review of the evidence. Molecular Psychiatry, 28, 3243-3256. https://doi.org/10.1038/s41380-022-01661-0

Organización Mundial de la Salud. (2021). Guidance on community mental health services: Promoting person-centred and rights-based approaches. https://www.who.int/publications/i/item/9789240025707

Organización Mundial de la Salud. (2022). World mental health report: Transforming mental health for all. https://www.who.int/publications/i/item/9789240049338

Organización Mundial de la Salud. (2023). Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders. https://www.who.int/publications/i/item/9789240084278

Organización Panamericana de la Salud. (2020). Desinstitucionalización de la atención psiquiátrica en América Latina y el Caribe. https://iris.paho.org/handle/10665.2/53027

Organización Panamericana de la Salud. (2020a). Salud mental: perfil del país - Ecuador. https://www.paho.org/es/documentos/salud-mental-perfil-pais-ecuador

Patel, V., Saxena, S., Lund, C., Thornicroft, G., Baingana, F., Bolton, P., Chisholm, D., Collins, P. Y., Cooper, J. L., Eaton, J., Herrman, H., Herzallah, M. M., Huang, Y., Jordans, M. J. D., Kleinman, A., Medina-Mora, M. E., Morgan, E., Niaz, U., Omigbodun, O., Prince, M., Rahman, A., Saraceno, B., Sarkar, B. K., De Silva, M., Singh, I., Stein, D. J., Sunkel, C., & Unützer, J. (2018). The Lancet Commission on global mental health and sustainable development. The Lancet, 392(10157), 1553-1598. https://doi.org/10.1016/S0140-6736(18)31612-X

Villalobos-Madriz, J. A., Serrano-Arias, B., Arguedas-Chacón, S., Zavaleta-Monestel, E., Rodríguez-Miranda, R., Chaverri-Fernández, J. M., & Covarrubias-Gómez, A. (2023). Prescribing trends in psychotropic medications among outpatients of a Latin American healthcare setting: A five-year retrospective study. Cureus, 15(4), e37832. https://doi.org/10.7759/cureus.37832

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Published

2023-11-27

How to Cite

Anchundia Talledo, G. D. (2023). Medicalization and Mental Health: The Role of Psychotropic Drugs in Psychological Suffering. Horizonte Cientifico International Journal, 1(1), 1-12. https://doi.org/10.64747/4wfywd19